• br Lipid modified cationic peptides induce ROS

  2020-08-30

  

  3.4. Lipid-modified cationic peptides induce ROS mPTP induction and mitochondrial depolarization typically involve increased cellular levels of ROS, triggering complex signaling cascades that lead to cell death [1]. To test whether this was happening during the treatment of EMT6/AR-1 cells with

• br The exploration of socioeconomic and demographic fac tors

  2020-08-28

  

  The exploration of socioeconomic and demographic fac-tors focused on 104 patients in the external validation set. A total of 62 (60%) had next of kin staying at their address. There was no significant difference in mean length of stay when the group that stayed less than 15 days was tested (test s

• PF 06700841 br biodegradation and their less hydrophobic cha

  2020-08-28

  

  biodegradation and their less hydrophobic character. Our work also demonstrates the potential of targeting non-canonical targets with non-viral combination nanoparticles. Our combination approach may also be able to be extended to polymeric nanoparticles that contain DNA [45] and other RNAs in add

• br Cell culture and reagents

  2020-08-28

  

  2.2. Cell culture and reagents Human gastric adenocarcinoma cell lines, AGS (ATCC, VA, USA) and MGC-803 (CBTCCCAS, Shanghai, China), and human stomach fibroblat line Hs738 (ATCC, VA, USA) were cultured in the complete DMEM (ATCC, VA, USA) with 10% fetal calf serum. Cisplatin and human IL-8 w

• br A br Sham br BCF br RCF

  2020-08-28

  

  A Sham BCF RCF H-Thymidine D Sham 231BrM BCF ns 3H-ThymidineCPM (normalizedtoSham) 3H-ThymidineCPM(normalizedtoSham) Vehicle Ethosuximide (normalizedtoSham) %decrease -10 ns hrs/day s/day hr Sham SKBrM3 BCF ns 3H-Thymidine CPM Vehicl

• br MicroRNAs miRNAs are small non coding RNAs

  2020-08-28

  

  MicroRNAs (miRNAs) are small non-coding RNAs (21 to 23 nu-cleotides) that play an important role in cancer processes like cell proliferation, apoptosis and metastasis (Cho, 2007). miRNAs regulate the expression of target genes by binding to 3′ untranslated regions (UTRs) of its target mRNAs and in

• br used for preoperative localization before biopsy Similarl

  2020-08-18

  

  511 used for preoperative localization before biopsy. Similarly, the 512 distance between the centroid of the suspicious lesions on 513 456 suspicious lesions and to eliminate false positives using length of minor axis of the lesion, M1, measured in terms of 515 457 reduced annular

• br temperature of solutions with different concentrations in

  2020-08-18

  

  temperature of solutions with different concentrations increased to 26.7, 34.6, 41.8, and 49.7 °C, respectively. In order to evaluate the photothermal stability of BPNs-PDA-PEG-PEITC, the 100 μg/mL solu-tion was irradiated with 808 nm NIR laser for 5 min. After turning off the NIR laser, the solut

• br Finally regarding potential confounders

  2020-08-18

  

  Finally, regarding potential confounders, several studies have shown that young women are more likely than older women to have never screened (Catarino et al., 2016; Were et al., 2011); with the lowest screening rates reported by women aged 20–29 years (42–51%), re-lative to those aged 45–54 years

• br JS has performed the assays and drafted

  2020-08-18

  

  JS has performed the assays and drafted the manuscript. DH, LHM, and WHC have participated in the study design and manuscript drafting. HZ has participated in study design, data analysis, and manuscript drafting. Funding sources The Mexican American Cohort receives funds collected purs

• br Williams CA Fernandez Alonso R Wang J Toth R

  2020-08-18

  

  [62] Williams CA, Fernandez-Alonso R, Wang J, Toth R, Gray NS, Findlay GM. Erk5 is a key regulator of naive-primed transition and embryonic stem cell identity. Cell Rep 2016;16:1820–8. [63] Gao C, Huang L, Long Y, Zheng J, Yang J, Pu S, Xie L. Y-39983, a selective Rho-kinase inhibitor, attenuates

• br medicine use among cancer

  2020-08-18

  

  medicine use among cancer survivors: A population-based study. J Cancer Surviv. 11. Tao W, Luo X, Cui B, Liang D, Wang C, Duan Y. Practice of traditional Chinese medicine for psycho-behavioral intervention improves quality of life in cancer pa-tients: A systematic review and meta-analysis. Onco

• br Andreassen CN Alsner J Genetic variants and normal

  2020-08-14

  

  [13] Andreassen CN, Alsner J. Genetic variants and normal tissue toxicity after radiotherapy: a systematic review. Radiother Oncol 2009;92:299–309. [14] West CM, Elliott RM, Burnet NG. The genomics revolution and radiotherapy. Clin Oncol 2007;19:470–80. https://doi.org/10.1016/j.radonc.2009.06.01

• br Methods We collected blood

  2020-08-14

  

  Methods: We collected 227 blood samples from 117 MBC patients. CTCs were enumerated using the CellSearch System. ccfDNAs were quantified by quantitative real-time polymerase chain reaction and Qubit fluorometer. The individual and joint effects of CTC and ccfDNA levels on patient progression-free

• br T Fransgaard et al br Fig STROBE flow diagram

  2020-08-14

  

  T. Fransgaard et al. Fig. 1. STROBE flow diagram. *Patients undergoing surgery for colorectal cancer with curative intent in the period January 1. 2003–July 1. 2015 ** n = 58 metformin, n = 69 other antidiabetic medication, n = 45 treatment with a combination of the different antidiabetic me

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