• br Highlights br d ARfl and ARv genomic

  2020-08-04

  

  Highlights d ARfl and ARv7 genomic binding is interdependent and colocalized d ARv7, unlike ARfl, preferentially represses transcription d Expression of ARv7-repressed Relebactam negatively correlates with recurrence d Re-expression of ARv7-repressed genes may serve as a biomarker of

• br Immunotoxin Therapy RIT Monotherapy and br Combination RI

  2020-07-30

  

  Immunotoxin Therapy (RIT) Monotherapy and Combination RIT-actinomycin D Therapy (P Beginning on Day 15 (Indicated by *). Actinomycin D Combination Therapy Is Significantly More Effective those undergoing vehicle treatment or oxaliplatin alone, there was no difference in tumor volume bet

• GW3965 Bebek G Bennett KL Funchain

  2020-07-28

  

  [21] Bebek G, Bennett KL, Funchain P, Cambell R, Seth R, Scharpf J, et al. Micro-biomic subprofiles and MDR1 promoter methylation in head and neck squa-mous cell carcinoma. Hum Mol Genet 2012;21:1557e65. [22] Hooper SJ, Crean SJ, Lewis MA, Spratt DA, Wade WG, Wilson MJ. Viable bac-teria present wit

• br may predominantly be causing side

  2020-07-28

  

   may predominantly be causing side effects with little therapeutic response. We observed that the huTGO1 and huTGO2 organoid lines expressed HER2, whereas huTGO4 and huTGO6 did not express this Cefepime protein (Figure 6A). This observation was contradictory to the pathologist’s observations

• br Effects of test compounds on cell cycle distribution

  2020-07-26

  

  2.2.4. Effects of test compounds on cell cycle distribution The effect of 11 on the cell cycle progression was evaluated by flow cytometry to validate the underlying mechanism of cell growth re-pression in PC-3 cells. The results of the experiment indicate that compound 11 and BIIB021 (2) caus

• br CAR NK cells per

  2020-07-04

  

  CAR-NK Temozolomide per injection. The mice were followed with serial weekly imaging to assess the tumor burden. (A) Effects of NK cells electroporated with NKG2Dp mRNA on tumor burden over time in mice with HCT116-Luc xenografts. Tumor burden over time by BLI is shown. Each mouse

• br volume Dmax Dmin Three weeks after

  2020-03-24

  

   volume = 0.5 × (Dmax × Dmin2). Three weeks after injection, the mice were sacrificed, and the primary tumours, livers and lungs were removed for further evaluation. 2.13. Statistical analysis All experiments were performed in triplicate. All data were statis-tically analyzed using SPSS ve

• br Conclusions br In summary our study provides proof

  2020-03-24

  

  4. Conclusions In summary, our study provides proof-of-concept for 7pep-M-RAP as a novel treatment modality to improve the therapeutic efficacy of chemotherapeutic nanomedicine. 7pep-M-RAP revealed synergistic anti-tumor effect with cytotoxic 7pep-M-PTX on MCF-7 breast cancer. Through ligand‒re

• A MTT analysis of AsPC pLXSN Adh

  2020-03-24

  

  A) MTT analysis of AsPC-1 + pLXSN (Adh.) HG-9-91-01 plated with the different NAX compounds. In Panel B, the IC50s are presented graphically. All of the experiments indicated in this figure were performed on the same day. These experiments were repeated 3 times and similar results were obtained.

• b iframe width height src https www youtube com

  2020-03-24

  

  r> In this study we investigated the role and the potential of targeting ABC transporters in PDAC therapy. We showe that a member of the ABCC family, ABCC3, is highly expressed in PDAC tumours and that its expression is dependent on mutation of TP53. We also show that ABCC3 is required for LPI-medi

• Sudhir Krishnaa br a National Centre

  2020-03-17

  

  Sudhir Krishnaa, a National Centre for Biological Sciences, Tata Institute of Fundamental Research, GKVK-UAS, Bangalore 560065, Karnataka, India b Department of Pathology, Kidwai Cancer Institute, Bangalore, India c The Babraham Institute, Cambridge, UK d School of Biological Sciences, Univers

• br Rosenthal SJ Chang JC Kovtun

  2020-03-17

  

  [6] Rosenthal SJ, Chang JC, Kovtun O, McBride JR, Tomlinson ID. Biocompatible quantum dots for biological applications. Chem Biol 2011;18:10–24. [7] Bohara RA, Thorat ND, Pawar SH. Role of functionalization: strategies to explore potential nano-bio applications of magnetic nanoparticles. RSC Ad

• br Conclusions br Metastatic lung cancer is

  2020-03-17

  

  7. Conclusions Metastatic lung cancer is a condition with poor prognosis in regards to its high morbidity and mortality. In this study, we aimed to analyze these various management modalities specifically for patients with metastatic lung cancer affecting the spine. Our sys-tematic review on th

• br Gene set analysis br To

  2020-03-17

  

  Gene set analysis To quantify the extent to which different groups of genes were enriched in a given metric (e.g., p values from a DE analysis), a gene set analysis (GSA) was performed. This type of analysis was applied in a number of situations throughout the study, and followed the same proce

• br Findings We established a prognostic panel designated as

  2019-11-12

  

  Findings: We established a prognostic panel, designated as tumour microenvironment risk score (TMRS), consisting of 100 genes. With specific risk score formulae, the TMRS panel possesses a strong ability to predict relapse-free survival and overall survival through both univariate and multivariate

131 records 6/9 page Previous Next First page Previous 5 pages 6789