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Anticancer effect of nor-wogonin (5, 7, 8-trihydroxyflavone) on human triple-negative breast cancer cells via downregulation of TAK1, NF-kB, and STAT3
Amer Ali Abd El-Hafeeza,b,c,*, Hazim O. Khalifad,e, Elham A.M. Mahdyf, Vikas Sharmag, Toru Hosoia, Pradipta Ghoshh,i,j, Koichiro Ozawaa, Monica M. Montanog,
Takashi Fujimurak, Ahmed R.N. Ibrahiml, Mohamed A.A. Abdelhamidm,n, Seung Pil Packn, Samia A. Shoumanc, Seiji Kawamotok
a Pharmacotherapy Department, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan
b Global Career Design Center, Hiroshima University, Hiroshima, Japan
c Pharmacology and Experimental Oncology Unit, Cancer Biology Department, National Cancer Institute, Cairo University, Cairo, Egypt
d Department of Pharmacology, Faculty of Veterinary Medicine, Kafrelsheikh University, Kafrelsheikh, Egypt
e Department of Infectious Diseases, Graduate School of Medicine, International University of Health and Welfare, Narita, Japan
f Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt
g Pharmacology Department, Case Western Reserve University School of Medicine, Cleveland, OH, USA
h Department of Medicine, University of California, San Diego, La Jolla, CA,USA
i Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA
j Moores Cancer Center, University of California, San Diego, La Jolla, CA, USA
k Hiroshima Research Center for Healthy Aging (HiHA), Department of Molecular Biotechnology, Graduate School of Advanced Sciences of Matter, Hiroshima University, Hiroshima, Japan l Department of Biochemistry, Faculty of Pharmacy, Minia University, Minia, Egypt
m Department of Botany and Microbiology, Faculty of Science, Minia University, Minia Egypt
n Department of Biotechnology and Bioinformatics, Korea University, Sejong, Republic of Korea